A personal endpoint can be created on a computer to transfer files between it and other endpoints. The software application Globus Connect Personal must be installed on a computer to create an endpoint on it and must be running to use the endpoint for a transfer.
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Download and install the Mac, Linux, or Windows version from the globus.org website, following instructions on the website. Note that the Globus website generates a "Setup Key", and during the installation process, this Setup Key must be entered when prompted for it. (On Linux, if a "Security Code" is required, enter the Setup Key for it.)
Reference: Globus website
When the installation is complete, a window like this shows up (on Linux), or a Globus icon shows up in the menu of running applications (on other systems):
On Linux and Mac systems, the above process didn't have a way to select which directory/directories should be used for the endpoint — it just automatically used the home directory. This can be changed after installation by going to File → Preferences (Linux), or from the Globus icon, Preferences... → Access (Mac):
the Preferences window, one or more directories that should be included in the endpoint can be selected. Once this is done, click "Save" (on Linux) or just close the Preferences window (on Mac), then click "Connect" in the main window (if necessary). The Windows installation process does allow this selection to be made during installation — if it needs to be changed later, that can be done through Options... → Access from the main menu.
To use the personal endpoint just made, "globusconnect" must be running. This is the same script that was used to install it and can be started from the command line or through a menu, depending on what system you're using. On Linux, this means that the above window must be open, and have a status of Connected, to use the personal endpoint. On other systems, the Globus icon must be in the menu of running applications and have a status of Connected.