HIFIASM

Overview

  • Hifiasm is a fast haplotype-resolved de novo assembler initially designed for PacBio HiFi reads. Its latest release could support the telomere-to-telomere assembly by utilizing ultralong Oxford Nanopore reads. Hifiasm produces arguably the best single-sample telomere-to-telomere assemblies combing HiFi, ultralong and Hi-C reads, and it is one of the best haplotype-resolved assemblers for the trio-binning assembly given parental short reads. For a human genome, hifiasm can produce the telomere-to-telomere assembly in one day.

Using

Use the module name hifiasm to discover versions available and to load the application.

Multicore

The hifiasm application allows you define multiple cores within calls by using the hifiasm -t options. See hifiasm -h for more information.